Dynamics of a cardiovascular model obtaining measurable pulsatile pressure output∗
نویسنده
چکیده
In this study, a lumped compartment cardiovascular model is developed to predict pulsatile pressures in the systemic and pulmonary circulation as well as in finger arteries. Essential compartments of the model include arterial and venous pulmonary, left and right ventricles, and arterial and venous systemic compartments. A pulsatile left ventricle is incorporated to be the source of pulse waves in the system. An aorta compartment is included to indicate pressure variations detected by baroreceptors acting as sensors in the cardiovascular system. Further, a finger artery is added as a typical site of pulsatile pressure measurements. In order to model the stiffness of heart muscles during exercise, a sigmoidal function dependent on heart rate is used to characterize the maximum left ventricular elastance. Numerical simulations of left-ventricular pressure and volume curves depicted its physiological dynamics. Moreover, the pulsatile cardiovascular model can be used to describe cardiovascular dynamics during rest and exercise conditions.
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